The Science

the science

At estrobio, we believe clarity is the highest form of efficacy. Our formulation is built not on wellness trends, but on over two decades of rigorous German clinical research and established European standards of care.

The Active Botanical: menofelis

estrobio is a single-ingredient, high-performance formulation featuring menofelis—a premium Siberian Rhubarb extract (Rheum rhaponticum L.).

Unlike typical menopausal supplements, menofelis is entirely hormone-free and contains no plant-based phytoestrogens. Instead, it works gently and progressively alongside your body’s existing natural pathways to provide targeted biological support where you need it most.

  • German Precision: Sourced, cultivated, and standardized under strict quality control parameters in Germany.

  • Pure Cleanliness: 100% vegan, drug-free, soy-free, and non-GMO.

Documented Relief: The 11 Signs

The efficacy of our active extract is anchored to the Menopause Rating Scale (MRS)—the global clinical standard used by medical professionals to measure menopausal well-being.

Clinical observations spanning more than 20 years show that the active compound in estrobio significantly supports the management of the 11 most common physical and lifestyle disruptions associated with perimenopause and menopause:

Physical Comfort Emotional Stability Daily Vitality
* Hot Flashes * Mood Changes * Fatigue
* Night Sweats * Irritability * Mental Fog & Concentration
* Heart Discomfort * Anxiety * Joint & Muscle Discomfort
* Sleeplessness * Physical Exhaustion


What to Expect: The Timeline

Because estrobio is a clean, drug-free botanical, it adapts to your system progressively. Consistency is the key to establishing balance.

  • Weeks 1 – 4 (The Initial Shift): The botanical begins interacting with your system. Many women report a noticeable initial shift in sudden temperature spikes and nighttime comfort.

  • Weeks 4 – 12 (Optimal Baseline): Continuous daily use establishes a steady baseline. Physical comfort, sleep stability, and daytime mental clarity become more sustained as the formula supports your daily rhythm.

† This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a healthcare professional before starting any new supplement ritual.